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</head>

<body lang=ES-AR link=blue vlink=purple style='tab-interval:35.4pt'>

<div class=WordSection1>
  <div align=center>
    
    <table class=MsoNormalTable border=0 cellspacing=5 cellpadding=0 width=0
 style='width:525.0pt;mso-cellspacing:3.7pt;mso-yfti-tbllook:1184;mso-padding-alt:
 0cm 0cm 0cm 0cm'>
 <tr style='mso-yfti-irow:0;mso-yfti-firstrow:yes'>
  <td colspan=2 valign=top style='padding:0cm 0cm 0cm 0cm'>
  <p class=MsoNormal align=center style='text-align:center'><span
  style='mso-fareast-font-family:"Times New Roman"'><img width=700
  id="_x0000_i1025"
  src="https://www.colfarma.info/colfarma/wp-content/uploads/headers/headers-rpvf.png">&nbsp;<o:p></o:p></span></p>
  </td>
 </tr>
 <tr style='mso-yfti-irow:1'>
  <td colspan=2 style='padding:0cm 0cm 0cm 0cm'>
  <p class=fecha>La Plata, 30 de NOVIEMBRE de 2021 – <a
  href="mailto:farmaceuticos@colfarma.org.ar">farmaceuticos@colfarma.org.ar</a>
  – <a href="http://www.colfarma.org.ar/">www.colfarma.org.ar</a></p>
  </td>
 </tr>
 <tr style='mso-yfti-irow:2'>
  <td colspan=2 valign=top style='padding:0cm 0cm 0cm 0cm'>
  <div class=MsoNormal align=center style='text-align:center'><span
  style='mso-fareast-font-family:"Times New Roman"'>
  <hr size=2 width="100%" align=center>
  </span></div>
  </td>
 </tr>
 <tr style='mso-yfti-irow:3'>
  <td colspan=2 style='padding:0cm 0cm 0cm 0cm'>
  <h5><span style='mso-fareast-font-family:"Times New Roman"'>ALERTA DE LA RPVF<o:p></o:p></span></h5>
  </td>
 </tr>
 <tr style='mso-yfti-irow:4'>
  <td width=227 valign=top style='width:112.5pt;padding:0cm 0cm 0cm 0cm'>
  <p class=MsoNormal><span style='mso-fareast-font-family:"Times New Roman"'><img
  border=0 width=150 height=120 id="_x0000_i1027"
  src="http://www.colfarma.info/colfarma/wp-content/uploads/2018/05/rpvf.jpg"><o:p></o:p></span></p>
  </td>
  <td width=487 style='width:409.5pt;padding:0cm 0cm 0cm 0cm'>
  <p><strong><span style='font-family:"Arial",sans-serif'>Red Provincial de
  Vigilancia Farmacéutica</span></strong><b><br>
  <strong><span style='font-family:"Arial",sans-serif'>Colegio de Farmacéuticos
  de la Pcia. de Bs. As.</span></strong></b>&nbsp;<br>
  <strong><span style='font-family:"Arial",sans-serif'>30/11/2021</span></strong>
  <strong><span style='font-family:"Arial",sans-serif'>Las alertas de la RPVF
  son preparadas para ser interpretadas por Farmacéuticos y otros profesionales
  de la salud.</span></strong><b><br>
  <strong><span style='font-family:"Arial",sans-serif'>Se autoriza la
  reproducción del presente alerta, citando la fuente.</span></strong></b></p>
  </td>
 </tr>
 <tr style='mso-yfti-irow:5'>
  <td colspan=2 style='padding:0cm 0cm 0cm 0cm'>
  <div class=MsoNormal align=center style='text-align:center'><span
  style='font-size:18.0pt;mso-fareast-font-family:"Times New Roman";color:black'>
  <hr size=2 width="100%" align=center>
  </span></div>
  </td>
 </tr>
 <tr style='mso-yfti-irow:6;height:142.5pt'>
  <td colspan=2 style='padding:0cm 0cm 0cm 0cm;height:142.5pt'>
  <p>Estimados Colegas: transcribimos la siguiente información de ANMAT </p>
  <p>&nbsp;</p>
  <h1><span style='mso-fareast-font-family:"Times New Roman"'>Advertencia sobre
  lote ilegítimo del producto SOLIRIS<o:p></o:p></span></h1>
  <p>La medida fue tomada por desconocerse sus condiciones de elaboración.<br>
  Publicado el lunes 29 de noviembre de 2021</p>
  <div class=MsoNormal align=center style='text-align:center'><span
  style='font-size:18.0pt;mso-fareast-font-family:"Times New Roman";color:black'>
  <hr size=1 width="100%" align=center>
  </span></div>
  <p>La ANMAT informa que, de acuerdo a lo informado por la empresa&nbsp;<strong><span
  style='font-family:"Arial",sans-serif'>MONTE VERDE S.A.</span></strong>&nbsp;-en
  su figura de representante de ALEXION para SOLIRIS® en territorio argentino-,
  han sido detectadas&nbsp;<strong><span style='font-family:"Arial",sans-serif'>unidades
  presuntamente falsificadas</span></strong>&nbsp;correspondientes la siguiente
  especialidad medicinal:</p>
  <ul type=disc>
   <li class=MsoNormal style='color:#363636;mso-margin-top-alt:auto;mso-margin-bottom-alt:
       auto;text-align:justify;mso-list:l0 level1 lfo1;tab-stops:list 36.0pt'><strong><span
       style='font-size:10.0pt;font-family:"Arial",sans-serif;mso-fareast-font-family:
       "Times New Roman"'>SOLIRIS/ECULIZUMAB 300 mg, vial 30 ml (10 mg/ml),
       concentrado para perfusión intravenosa. LOTE 1001381 – Vto MAR/2022</span></strong><span
       style='font-size:10.0pt;font-family:"Arial",sans-serif;mso-fareast-font-family:
       "Times New Roman"'><o:p></o:p></span></li>
   <li class=MsoNormal style='color:#363636;mso-margin-top-alt:auto;mso-margin-bottom-alt:
       auto;text-align:justify;mso-list:l0 level1 lfo1;tab-stops:list 36.0pt'><strong><span
       style='font-size:10.0pt;font-family:"Arial",sans-serif;mso-fareast-font-family:
       "Times New Roman"'>SOLIRIS/ECULIZUMAB 300 mg, vial 30 ml (10 mg/ml),
       concentrado para perfusión intravenosa. LOTE 1012401 – Vto SEP/2022</span></strong><span
       style='font-size:10.0pt;font-family:"Arial",sans-serif;mso-fareast-font-family:
       "Times New Roman"'><o:p></o:p></span></li>
  </ul>
  <p>El producto citado ingresa al país bajo el&nbsp;<strong><span
  style='font-family:"Arial",sans-serif'>Régimen de Acceso de Excepción de Medicamentos
  No Registrados – RAEM (ex Uso Compasivo)</span></strong>&nbsp;por no
  encontrarse inscripto ante esta Administración Nacional al día de la fecha.<br>
  Al desconocerse las condiciones en las que fueron elaborados, se recomienda a
  la población que tenga en su poder productos de los lotes mencionados,&nbsp;<strong><span
  style='font-family:"Arial",sans-serif'>no utilizarlos y ponerse en contacto a
  la brevedad</span></strong>&nbsp;con la Dirección de Evaluación y Gestión y
  Monitoreo de Productos para la Salud al correo electrónico&nbsp;<a
  href="mailto:pesquisa@anmat.gov.ar">pesquisa@anmat.gov.ar</a>.</p>
  <p>Fuente: <a
  href="https://www.argentina.gob.ar/noticias/advertencia-sobre-lote-ilegitimo-del-producto-soliris">https://www.argentina.gob.ar/noticias/advertencia-sobre-lote-ilegitimo-del-producto-soliris</a></p>
  <p>&nbsp;</p>
  <h1><span style='mso-fareast-font-family:"Times New Roman"'>ANMAT advierte
  sobre preservativos falsificados marca Prime<o:p></o:p></span></h1>
  <p>Han sido detectadas unidades falsificadas correspondientes a lotes de tres
  variedades de dicho producto.<br>
  Publicado el lunes 29 de noviembre de 2021</p>
  <div class=MsoNormal align=center style='text-align:center'><span
  style='font-size:18.0pt;mso-fareast-font-family:"Times New Roman";color:black'>
  <hr size=1 width="100%" align=center>
  </span></div>
  <p>La ANMAT comunica que, de acuerdo a lo informado por la empresa BUHL S.A.
  titular del producto PM1315-20 Preservativo Masculino de Latex Caucho Natural
  marca “PRIME ®”, han sido detectadas unidades falsificadas correspondientes a
  las siguientes variedades:</p>
  <ul type=disc>
   <li class=MsoNormal style='color:#363636;mso-margin-top-alt:auto;mso-margin-bottom-alt:
       auto;text-align:justify;mso-list:l1 level1 lfo2;tab-stops:list 36.0pt'><strong><span
       style='font-size:10.0pt;font-family:"Arial",sans-serif;mso-fareast-font-family:
       "Times New Roman"'>PRIME® Texturado – Caja por 3 preservativos - Lote PL
       1902M843 – VTO: OCT/23</span></strong><span style='font-size:10.0pt;
       font-family:"Arial",sans-serif;mso-fareast-font-family:"Times New Roman"'><o:p></o:p></span></li>
   <li class=MsoNormal style='color:#363636;mso-margin-top-alt:auto;mso-margin-bottom-alt:
       auto;text-align:justify;mso-list:l1 level1 lfo2;tab-stops:list 36.0pt'><strong><span
       style='font-size:10.0pt;font-family:"Arial",sans-serif;mso-fareast-font-family:
       "Times New Roman"'>PRIME® Tachas Lote - Caja por 3 preservativos PL
       1906N142 – VTO: OCT/23</span></strong><span style='font-size:10.0pt;
       font-family:"Arial",sans-serif;mso-fareast-font-family:"Times New Roman"'><o:p></o:p></span></li>
   <li class=MsoNormal style='color:#363636;mso-margin-top-alt:auto;mso-margin-bottom-alt:
       auto;text-align:justify;mso-list:l1 level1 lfo2;tab-stops:list 36.0pt'><strong><span
       style='font-size:10.0pt;font-family:"Arial",sans-serif;mso-fareast-font-family:
       "Times New Roman"'>PRIME® Superfino - Caja por 3 preservativos - Lote PL
       1907N189 – VTO: OCT/23</span></strong><span style='font-size:10.0pt;
       font-family:"Arial",sans-serif;mso-fareast-font-family:"Times New Roman"'><o:p></o:p></span></li>
  </ul>
  <p>Al desconocerse las condiciones en las que fueron elaborados, se
  recomienda a la población que tenga en su poder productos de los lotes con
  las características mencionadas, no utilizarlos y ponerse en contacto a la
  brevedad con&nbsp;<a href="mailto:pesquisa@anmat.gov.ar">pesquisa@anmat.gov.ar</a>.</p>
  <p class=MsoNormal align=center style='text-align:center'><span
  style='font-size:18.0pt;mso-fareast-font-family:"Times New Roman";color:black'><img
  border=0 width=700 id="_x0000_i1031"
  src="https://www.colfarma.info/colfarma/wp-content/uploads/2021/11/prime-falso.jpg"><o:p></o:p></span></p>
  <h1><span style='mso-fareast-font-family:"Times New Roman"'><img border=0
  width=700 id="_x0000_i1032"
  src="https://www.colfarma.info/colfarma/wp-content/uploads/2021/11/prime-falso-1.jpg"><o:p></o:p></span></h1>
  <p>&nbsp;</p>
  <p>Fuente: <a
  href="https://www.argentina.gob.ar/noticias/anmat-advierte-sobre-preservativos-falsificados-marca-prime">https://www.argentina.gob.ar/noticias/anmat-advierte-sobre-preservativos-falsificados-marca-prime</a></p>
  </td>
 </tr>
 <tr style='mso-yfti-irow:7'>
  <td colspan=2 style='padding:0cm 0cm 0cm 0cm'>
  <div class=MsoNormal align=center style='text-align:center'><span
  style='mso-fareast-font-family:"Times New Roman"'>
  <hr size=2 width="100%" align=center>
  </span></div>
  </td>
 </tr>
 <tr style='mso-yfti-irow:8'>
  <td colspan=2 style='padding:0cm 0cm 0cm 0cm'>
  <p class=MsoNormal align=center style='text-align:center'><span
  style='mso-fareast-font-family:"Times New Roman"'><img border=0 width=188
  height=68 id="_x0000_i1034"
  src="http://www.colfarma.info/colfarma/wp-content/uploads/2018/03/image003-1.png"
  align=center><o:p></o:p></span></p>
  </td>
 </tr>
 <tr style='mso-yfti-irow:9'>
  <td colspan=2 valign=top style='padding:0cm 0cm 0cm 0cm'>
  <p class=MsoNormal align=center style='text-align:center'><strong><span
  style='font-size:9.0pt;font-family:"Arial",sans-serif;mso-fareast-font-family:
  "Times New Roman";color:#1E4273'>Farm. Isabel Reinoso</span></strong><span
  style='font-size:9.0pt;font-family:"Arial",sans-serif;mso-fareast-font-family:
  "Times New Roman";color:#1E4273'><br>
  Presidente<br>
  Red Provincial de Vigilancia Farmacéutica<br>
  Colegio de Farmacéuticos de la Pcia. de Bs. As. <o:p></o:p></span></p>
  </td>
 </tr>
 <tr style='mso-yfti-irow:10'>
  <td colspan=2 valign=top style='padding:0cm 0cm 0cm 0cm'>
  <div class=MsoNormal align=center style='text-align:center'><span
  style='mso-fareast-font-family:"Times New Roman"'>
  <hr size=2 width="100%" align=center>
  </span></div>
  </td>
 </tr>
 <tr style='mso-yfti-irow:11;mso-yfti-lastrow:yes'>
  <td colspan=2 valign=top style='padding:0cm 0cm 0cm 0cm'>
  <p class=pie><strong><span style='font-family:"Arial",sans-serif'>COLEGIO DE
  FARMACÉUTICOS DE LA PROVINCIA DE BUENOS AIRES</span></strong><br>
  Calle 5 Nro 966 (1900) La Plata<br>
  Telefax (0221) 4290900 (líneas rotativas)</p>
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